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The 100 Most Disruptive Pouch Papers

Ranked by the disruption index (CD index; Funk & Owen-Smith 2017), a citation-network measure of how strongly a paper eclipses the prior work it builds on rather than reinforcing it. Computed locally from the NIH Open Citation Collection across 12,473 curated pouch articles.

#Paper CD index Citations
1Surgical treatment of toxic megacolon. Ileostomy and colostomy to prepare patients for colectomy.
Turnbull — American journal of surgery · 1971
+0.730120
2Three hundred cases of diffuse ulcerative colitis treated by total colectomy and ileo-rectal anastomosis.
Aylett — British medical journal · 1966
+0.636137
3Intra-abdominal "reservoir" in patients with permanent ileostomy. Preliminary observations on a procedure resulting in fecal "continence" in five ileostomy patients.
Kock — Archives of surgery (Chicago, Ill. : 1960) · 1969
+0.589474
4Laparoscopic total proctocolectomy with creation of ileostomy for ulcerative colitis: report of two cases.
Peters — J Laparoendosc Surg · 1992
+0.49663
5Proctocolectomy without ileostomy for ulcerative colitis.
Parks A — Br Med J · 1978
+0.4001,023
6Eflornithine plus Sulindac for Prevention of Progression in Familial Adenomatous Polyposis
Burke — N Engl J Med · 2020
+0.37153
7Ulcerative colitis with relative sparing of the rectum. Clinical features, histology, and prognosis.
Spiliadis — Diseases of the colon and rectum · 1987
+0.35648
8Ileostomy for ulcerative colitis; technique, complications, and management.
WARREN — Surgery, gynecology & obstetrics · 1951
+0.314136
9Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease.
Hellers — Gut · 1980
+0.292362
10Life expectancy after colectomy and ileorectal anastomosis for familial adenomatous polyposis.
Nugent — Diseases of the colon and rectum · 1993
+0.270145
11Balloon dilatation of biliary strictures through a choledochojejuno-cutaneous fistula.
Hutson — Annals of surgery · 1984
+0.24189
12Predicting Outcomes in Pediatric Ulcerative Colitis for Management Optimization: Systematic Review and Consensus Statements From the Pediatric Inflammatory Bowel Disease-Ahead Program.
Orlanski-Meyer — Gastroenterology · 2021
+0.21846
13Dysplasia-associated lesion or mass (DALM) detected by colonoscopy in long-standing ulcerative colitis: an indication for colectomy.
Blackstone — Gastroenterology · 1981
+0.207412
14The relative significance of preoperative oral antibiotics, mechanical bowel preparation, and preoperative peritoneal contamination in the avoidance of sepsis after radical surgery for ulcerative colitis and Crohn's disease of the large bowel.
Barker — The British journal of surgery · 1971
+0.20557
15Treatment of colorectal and ileoanal anastomotic sinuses
Whitlow — Dis Colon Rectum · 1997
+0.16655
16Comparison of handsewn with stapled loop ileostomy closures
Hull — Dis Colon Rectum · 1996
+0.16158
17Hyperalimentation as primary therapy for inflammatory bowel disease.
Fischer — American journal of surgery · 1973
+0.154153
18Autosuture GIA gun: a new application in the treatment of hypopharyngeal diverticula.
Martin-Hirsch — The Journal of laryngology and otology · 1993
+0.14978
19Course of ulcerative colitis: analysis of changes in disease activity over years.
Langholz — Gastroenterology · 1994
+0.142523
20Repair of persistent perineal sinuses by means of a pedicle flap of musculus gracilis. Case report.
Bartholdson — Scand J Plast Reconstr Surg · 1975
+0.13541
21Surgical measures as supplements to the management of idiopathic ulcerative colitis; cancer, cirrhosis, and arthritis as frequent complications.
DENNIS — Surgery · 1952
+0.13384
22The treatment of acute toxic ulcerative colitis by ileostomy and simultaneous colectomy.
CRILE — Gastroenterology · 1951
+0.13050
23Proctitis and colitis following diversion of the fecal stream.
Glotzer — Gastroenterology · 1981
+0.126239
24Quality of life after prophylactic colectomy and ileorectal anastomosis in patients with familial adenomatous polyposis
Church — Dis Colon Rectum · 1996
+0.12453
25Fate of the rectal mucosa after rectal mucosectomy and ileoanal anastomosis.
Heppell — Dis Colon Rectum · 1983
+0.121105
26Short-chain fatty acids in the human colon: relation to gastrointestinal health and disease
Mortensen — Scand J Gastroenterol Suppl · 1996
+0.118332
27Portal bacteraemia in cases of ulcerative colitis submitted to colectomy.
Eade — Lancet (London, England) · 1969
+0.11890
28An innovative technique for colorectal specimen retrieval: a new era of "natural orifice specimen extraction" (N.O.S.E)
Palanivelu — Dis Colon Rectum · 2008
+0.117112
29Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications.
Riddell — Human pathology · 1983
+0.1131,579
30Cyclosporine in severe ulcerative colitis refractory to steroid therapy.
Lichtiger — The New England journal of medicine · 1994
+0.1101,416
31Serum antibodies to Bacteroides species in chronic inflammatory bowel disease.
Tvede — Scandinavian journal of gastroenterology · 1983
+0.10942
32Thrombocytosis in chronic inflammatory bowel disease.
Morowitz — Annals of internal medicine · 1968
+0.106169
33Choice of operation for the toxic megacolon phase of nonspecific ulcerative colitis.
Turnbull — The Surgical clinics of North America · 1970
+0.10642
34Mortality in patients with familial adenomatous polyposis.
Arvanitis — Diseases of the colon and rectum · 1990
+0.105324
35The fate of ileorectal anastomosis in Crohn's disease.
Burman — Gut · 1971
+0.10457
36Subtotal colectomy for ulcerative colitis: complications related to the rectal remnant.
Carter F — Dis Colon Rectum · 1991
+0.10175
37Yang needle tunneling technique in creating antireflux and continent mechanisms.
— The Journal of urology · 1993
+0.100138
38Influence on sexual function of abdominoperineal resection for ulcerative colitis.
STAHLGREN — The New England journal of medicine · 1958
+0.10040
39The extra-intestinal complications of Crohn's disease and ulcerative colitis: a study of 700 patients.
Greenstein — Medicine · 1976
+0.0991,060
40Social prognosis in patients with ulcerative colitis.
Hendriksen — British medical journal · 1980
+0.09751
41Single-patient randomised clinical trial. Use in determining optimum treatment for patient with inflammation of Kock continent ileostomy reservoir
McLeod — Lancet · 1986
+0.09367
42Endoscopic gastroduodenal polypectomy.
— Annals of surgery · 1984
+0.09265
43Laparoscopically assisted ileocolectomy in Crohn's disease.
Milsom — Surgical laparoscopy & endoscopy · 1993
+0.09177
44Quantitative method for measuring adjuvant-induced granuloma angiogenesis in insulin-treated diabetic mice.
Kimura — Journal of pharmacobio-dynamics · 1986
+0.09144
45Nerve-sparing robot-assisted radical cystoprostatectomy and urinary diversion.
— BJU international · 2003
+0.091438
46Aetiology of disruption of intestinal anastomoses.
Irvin — The British journal of surgery · 1973
+0.088326
47Preliminary experience with laparoscopic intestinal surgery for Crohn's disease.
Ludwig — American journal of surgery · 1996
+0.08499
48A repair operation for recurrent dislocation of peroneal tendons.
Das De — J Bone Joint Surg Br · 1985
+0.08259
49Colpocystodefecography.
Hock — Diseases of the colon and rectum · 1993
+0.08178
50Small bowel ischemia after Roux-en-Y gastric bypass complicated by pregnancy: a case report.
— The American surgeon · 2005
+0.07944
51Laparoscopic surgery for inflammatory bowel disease
Liu — Am Surg · 1995
+0.07845
52Unexplained bronchopulmonary disease with inflammatory bowel disease.
Kraft — Archives of internal medicine · 1976
+0.073200
53Readmissions after colorectal surgery cannot be predicted.
Azimuddin — Diseases of the colon and rectum · 2001
+0.07277
54Results of surgery for inflammatory bowel disease: a further survey of one hospital region.
Ritchie — British medical journal · 1974
+0.06953
55Regression of rectal adenomas after colectomy and ileorectal anastomosis for familial adenomatous polyposis.
Nicholls — British medical journal (Clinical research ed.) · 1988
+0.06943
56Effect of neostigmine on integrity of ileorectal anastomoses.
Bell — British medical journal · 1968
+0.06657
57Epidemiological study of ulcerative proctocolitis in Indian migrants and the indigenous population of Leicestershire.
Probert — Gut · 1992
+0.064218
58The fate of the rectal stump after subtotal colectomy for ulcerative colitis.
Oakley — Diseases of the colon and rectum · 1985
+0.06247
59Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum.
Rutgeerts — Lancet (London, England) · 1991
+0.060594
60Urinary diversion via a continent ileal reservoir: clinical results in 12 patients.
Kock — The Journal of urology · 1982
+0.058457
61Clinical outcome of ulcerative colitis in children.
Hyams — The Journal of pediatrics · 1996
+0.058125
62An assessment of inflammation in the reservoir after restorative proctocolectomy with ileoanal ileal reservoir
Moskowitz — Int J Colorectal Dis · 1986
+0.058299
63Laparoscopic adjustable gastric banding.
Belachew — World journal of surgery · 1998
+0.057203
64Safety of the temporary loop ileostomy
Hallböök — Colorectal Dis · 2002
+0.05662
65PLACE OF A DOUBLE-BARRELLED ILEOSTOMY IN ULCERATIVE COLITIS AND CROHN'S DISEASE OF THE COLON: A PRELIMINARY REPORT.
TRUELOVE — British medical journal · 1965
+0.05666
66Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies.
Ng — 2017
+0.0564,514
67Adenocarcinoma of the ileostomy occurring after colectomy for ulcerative colitis: report of a case.
Sigler — Diseases of the colon and rectum · 1969
+0.05558
68Quality of life after radical cystectomy for bladder cancer in patients with an ileal conduit, cutaneous or urethral kock pouch.
— The Journal of urology · 1999
+0.053149
69Prospective study of the effect of resection of the rectum on male sexual function
Fazio — World J Surg · 1980
+0.05277
70Laparoscopic total abdominal colectomy. A prospective trial
Wexner — Dis Colon Rectum · 1992
+0.050191
71Let sleeping dogs lie: role of the omentum in the ileal pouch-anal anastomosis procedure
Ambroze — Dis Colon Rectum · 1991
+0.05040
72Optum Labs: building a novel node in the learning health care system.
Wallace Paul — Health Aff (Millwood) · 2014
+0.050350
73Surgery of the large bowel for emergent conditions. Staged vs primary resection.
— Archives of surgery (Chicago, Ill. : 1960) · 1969
+0.04844
74Ileal pouch-anal anastomosis without temporary, diverting ileostomy
Metcalf — Dis Colon Rectum · 1986
+0.04754
75Mucosal morphology, bacteriology, and absorption in intra-abdominal ileostomy reservoir.
Philipson — Scand J Gastroenterol · 1975
+0.04782
76Long term prognosis in ulcerative colitis--based on results from a regional patient group from the county of Copenhagen.
Hendriksen — Gut · 1985
+0.047219
77Portal hypertension and bleeding ileal varices after colectomy and ileostomy for chronic ulcerative colitis.
Cameron — Gut · 1970
+0.04649
78Ulcerative colitis and colorectal cancer. A population-based study.
Ekbom — The New England journal of medicine · 1990
+0.0461,432
79Results of the pelvic-pouch procedure in patients with Crohn's disease.
Deutsch A — Dis Colon Rectum · 1991
+0.044132
80Laparoscopic total abdominal colectomy with ileorectal anastomosis for familial adenomatous polyposis.
Milsom — Diseases of the colon and rectum · 1997
+0.04353
81Early complications following surgical treatment for Crohn's disease.
Heimann — Annals of surgery · 1985
+0.04277
82Long-term complications and prognosis following major surgery for ulcerative colitis.
Watts — The British journal of surgery · 1966
+0.041181
83Centralized registration, prophylactic examination, and treatment results in improved prognosis in familial adenomatous polyposis. Results from the Danish Polyposis Register.
Bülow — Scandinavian journal of gastroenterology · 1995
+0.03976
84Probiotics, immunomodulation, and health benefits
Gill — Adv Exp Med Biol · 2008
+0.039123
85Overlap in the spectrum of non-specific inflammatory bowel disease--'colitis indeterminate'.
Price — Journal of clinical pathology · 1978
+0.037264
86Prognosis after surgery for colonic Crohn's disease.
Andrews H — Br J Surg · 1989
+0.03654
87Spontaneous resolution of rectal polyps in patients with familial polyposis following abdominal colectomy and ileorectal anastomosis.
— Diseases of the colon and rectum · 1988
+0.03658
88Review article: short chain fatty acids in health and disease
Cook — Aliment Pharmacol Ther · 1998
+0.034396
89Self-reported food intolerance in chronic inflammatory bowel disease.
Ballegaard — Scandinavian journal of gastroenterology · 1997
+0.03370
90Relationship of backwash ileitis to ileal pouchitis after ileal pouch-anal anastomosis
Gustavsson — Dis Colon Rectum · 1987
+0.03371
91Three years' experience with an ileal low pressure bladder substitute.
— British journal of urology · 1989
+0.033168
92Comparison of bowel function after ileorectal anastomosis for ulcerative colitis and colonic polyposis.
Newton — Gut · 1975
+0.03362
93Perineal sinus after removal of the rectum. Occlusion with fibrin adhesive.
— American journal of surgery · 1983
+0.03243
94Proceedings: Intravenous hyperalimentation in the treatment of inflammatory diseases of the bowel.
— Archives of surgery (Chicago, Ill. : 1960) · 1974
+0.03289
95Pouchitis associated with primary cytomegalovirus infection
Moonka — Am J Gastroenterol · 1998
+0.03067
96Patient characteristics associated with venous thromboembolic events: a cohort study using pooled electronic health record data.
Kaelber David — J Am Med Inform Assoc · 2012
+0.030112
97Changes in the bidirectional sodium flux across the intestinal mucosa in Crohn's disease.
Allan — Gut · 1975
+0.03047
98Very low intraluminal colonic pH in patients with active ulcerative colitis.
Fallingborg — Digestive diseases and sciences · 1993
+0.030172
99Long-term ileostomy complications in patients with ulcerative colitis and Crohn's disease.
Carlstedt — Int J Colorectal Dis · 1987
+0.02957
100Tubulovillous adenomas in a continent ileostomy after proctocolectomy for familial polyposis
Beart — Dig Dis Sci · 1982
+0.02942

* Disruption index (CD) is unreliable for papers published within the last 5 years (insufficient forward-citation window); such papers are excluded from this ranking. CD ranges from +1 (fully disruptive) to -1 (fully consolidating).

Educational and research-reference use only. Bibliometric analysis only; abstracts and full text are not reproduced. Disruption index computed from the NIH Open Citation Collection (NIH-OCC); each entry links to its record.